Litaf^tm1Samr
Targeted Allele Detail

Summary

• Symbol: Litaf^tm1Samr
• Name: LPS-induced TN factor; targeted mutation 1, Salomon Amar
• MGI ID: MGI:3687962
• Synonyms: LITAF fl
• Gene: Litaf Location: Chr16:10777137-10810985 bp, - strand Genetic Position: Chr16, 6.28 cM, cytoband B1-B3
• Alliance: Litaf^tm1Samr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:113750
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a neo into intron 1 and loxP sites to flank the neo and exons 2 and 3. (J:113750)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Litaf Mutation: 14 strains or lines available

References

• Original: J:113750 Tang X, et al., LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways. Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13777-82
• All: 3 reference(s)