H2-DMa^tm1Liz
Targeted Allele Detail

Summary

• Symbol: H2-DMa^tm1Liz
• Name: histocompatibility 2, class II, locus DMa; targeted mutation 1, Elizabeth K Bikoff
• MGI ID: MGI:3688433
• Gene: H2-DMa Location: Chr17:34338667-34358075 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: H2-DMa^tm1Liz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:113714
• Parent Cell Line: BALB/c-I (ES Cell)
• Strain of Origin: BALB/cJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace all of exon 1 and part of exon 2 with a neomycin resistance cassette. (J:113714)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H2-DMa Mutation: 27 strains or lines available

References

• Original: J:113714 Bikoff EK, et al., Relaxed DM requirements during class II peptide loading and CD4+ T cell maturation in BALB/c mice. J Immunol. 2001 Apr 15;166(8):5087-98
• All: 5 reference(s)