Tg(Myh6-Gja7)927Kaya
Transgene Detail

Summary

• Symbol: Tg(Myh6-Gja7)927Kaya
• Name: transgene insertion 927, Kathryn A Yamada
• MGI ID: MGI:3688513
• Synonyms: Cx45OE
• Transgene: Tg(Myh6-Gja7)927Kaya Location: unknown
• Alliance: Tg(Myh6-Gja7)927Kaya page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Gja7)927Kaya expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Gjc1 (MGI:95718)

• Mutation details: This transgene consists of the coding sequence (nt 452-1642) of Gja7 under the control of the alpha-myosin heavy chain promoter, resulting in cardiac specific overexpression of Gja7. Three other lines were made with similar phenotypes. (J:104791)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:104791 Betsuyaku T, et al., Overexpression of cardiac connexin45 increases susceptibility to ventricular tachyarrhythmias in vivo. Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H163-71
• All: 2 reference(s)