Btf3^Gt(ROSA)1Bhr
Gene trapped Allele Detail

Summary

• Symbol: Btf3^Gt(ROSA)1Bhr
• Name: basic transcription factor 3; gene trap mutation 1, Richard R Behringer
• MGI ID: MGI:3688730
• Synonyms: ROSA beta-geo 3-7
• Gene: Btf3 Location: Chr13:98446405-98453514 bp, - strand Genetic Position: Chr13, 51.92 cM, cytoband D1
• Alliance: Btf3^Gt(ROSA)1Bhr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:28132
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector integrated between exons 3 and 4 of the gene. Beta-galactosidase is expressed from this allele in a subset of tissues, while the endogenous gene is expressed ubiquitously. (J:28132)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Btf3 Mutation: 34 strains or lines available

Notes

Genbank: S79537, S79538

References

• Original: J:28132 Deng JM, et al., An insertional mutation in the BTF3 transcription factor gene leads to an early postimplantation lethality in mice. Transgenic Res. 1995 Jul;4(4):264-9
• All: 1 reference(s)