Pgr^tm1.2Mlia
Targeted Allele Detail

Summary

• Symbol: Pgr^tm1.2Mlia
• Name: progesterone receptor; targeted mutation 1.2, M Luisa Iruela-Arispe
• MGI ID: MGI:3689427
• Synonyms: PRKO
• Gene: Pgr Location: Chr9:8899834-8968612 bp, + strand Genetic Position: Chr9, 2.46 cM
• Alliance: Pgr^tm1.2Mlia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:114465
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 1 was removed via cre mediated recombination. Absence of isoforms A and B was confirmed by Western blot analysis. (J:114465)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgr Mutation: 75 strains or lines available

References

• Original: J:114465 Hashimoto-Partyka MK, et al., Generation of a mouse for conditional excision of progesterone receptor. Genesis. 2006 Aug;44(8):391-5
• All: 3 reference(s)