Tg(UCP3,UCP2)1Ful
Transgene Detail

Summary

• Symbol: Tg(UCP3,UCP2)1Ful
• Name: transgene insertion 1, Charles A Fuller
• MGI ID: MGI:3689922
• Synonyms: UCP2/3
• Transgene: Tg(UCP3,UCP2)1Ful Location: unknown
• Alliance: Tg(UCP3,UCP2)1Ful page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: An 80-kb human bacterial artificial chromosome (BAC) containing all of the UCP2 and UCP3 genes was used to create the transgenic mice. The BAC contained UCP3 and then UCP2 in a 5'-3' orientation. An additional ~40 kb of sequence was 5' of UCP3 and there was 8 kb of sequence 3' to UCP2. (J:114746)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(UCP3,UCP2)1Ful

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:114746 Fuller PM, et al., Effects of 2-G exposure on temperature regulation, circadian rhythms, and adiposity in UCP2/3 transgenic mice. J Appl Physiol. 2000 Oct;89(4):1491-8
• All: 6 reference(s)