Has3^tm1Daq
Targeted Allele Detail

Summary

• Symbol: Has3^tm1Daq
• Name: hyaluronan synthase 3; targeted mutation 1, Deborah A Quinn
• MGI ID: MGI:3689925
• Synonyms: Has3^-
• Gene: Has3 Location: Chr8:107596874-107609534 bp, + strand Genetic Position: Chr8, 53.28 cM
• Alliance: Has3^tm1Daq page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:114249
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A vector was designed to remove a large portion of exon 4, which encodes 100 amino acids in the catalyitic region. (J:114249)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Has3 Mutation: 16 strains or lines available

References

• Original: J:114249 Bai KJ, et al., The role of hyaluronan synthase 3 in ventilator-induced lung injury. Am J Respir Crit Care Med. 2005 Jul 1;172(1):92-8
• All: 14 reference(s)