Nkx3-1^tm1(cre)Wez
Targeted Allele Detail

Summary

• Symbol: Nkx3-1^tm1(cre)Wez
• Name: NK3 homeobox 1; targeted mutation 1, Warren E Zimmer
• MGI ID: MGI:3689997
• Synonyms: Nkx3.1-cre
• Gene: Nkx3-1 Location: Chr14:69428141-69432107 bp, + strand Genetic Position: Chr14, 36.02 cM
• Alliance: Nkx3-1^tm1(cre)Wez page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:114573
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Nkx3-1^tm1(cre)Wez expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nkx3-1 (MGI:97352)

• Mutation details: A cre-PGK-neo cassette was inserted into the second exon of the locus, deleting ~630 bp spanning from the homeodomain to the end of the protein. (J:114573)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nkx3-1 (mouse) Summary of all recombinase alleles driven by Nkx3-1. Alliance mouse Nkx3-1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nkx3-1 Mutation: 38 strains or lines available

References

• Original: J:114573 Stanfel MN, et al., Expression of an Nkx3.1-CRE gene using ROSA26 reporter mice. Genesis. 2006 Nov;44(11):550-5
• All: 1 reference(s)