Il2rg^tm1Krf
Targeted Allele Detail

Summary

• Symbol: Il2rg^tm1Krf
• Name: interleukin 2 receptor, gamma chain; targeted mutation 1, Paul Krimpenfort
• MGI ID: MGI:3690461
• Synonyms: gammac, IL-2Rgammac^-
• Gene: Il2rg Location: ChrX:100307991-100311861 bp, - strand Genetic Position: ChrX, 43.9 cM
• Alliance: Il2rg^tm1Krf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123682
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• All coding exons are replaced by a pgk-hygromycin cassette. (J:114561)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il2rg Mutation: 179 strains or lines available

References

• Original: J:123682 Blom B, et al., The role of the common gamma chain of the IL-2, IL-4, IL-7 and IL-15 receptors in development of lymphocytes, constitutive of Bcl-2 does not rescue the developmental defects in gamma common-defiecent mice, in Cytokines and Growth Factors in Blood Transfusion. 1997:3-12.
• All: 11 reference(s)