Maea^Gt(XG702)Byg
Gene trapped Allele Detail

Summary

• Symbol: Maea^Gt(XG702)Byg
• Name: macrophage erythroblast attacher; gene trap XG702, BayGenomics
• MGI ID: MGI:3691058
• Synonyms: Emp^-
• Gene: Maea Location: Chr5:33492916-33530638 bp, + strand Genetic Position: Chr5, 17.55 cM, cytoband B1
• Alliance: Maea^Gt(XG702)Byg page

Mutation origin

• Mutant Cell Line: XG702
• Germline Transmission: Earliest citation of germline transmission: J:114865
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• A gene trap vector containing a beta-geo was inserted into intron 1 of the locus. (J:114865)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XG702	CC200121 ; (MGI Seq Detail)	5' RACE	Chr5:33492897-33492986 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  7 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Maea Mutation: 40 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:114865 Soni S, et al., Absence of erythroblast macrophage protein (Emp) leads to failure of erythroblast nuclear extrusion. J Biol Chem. 2006 Jul 21;281(29):20181-9
• All: 2 reference(s)