Gpbar1^tm1Ktan
Targeted Allele Detail

Summary

• Symbol: Gpbar1^tm1Ktan
• Name: G protein-coupled bile acid receptor 1; targeted mutation 1, Kenichi Tanaka
• MGI ID: MGI:3691111
• Synonyms: Gpbar1^-
• Gene: Gpbar1 Location: Chr1:74317709-74318783 bp, + strand Genetic Position: Chr1, 38.53 cM
• Alliance: Gpbar1^tm1Ktan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:114971
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 2 was disrupted by the insertion of a neomycin resistance gene. Northern blot failed to detect transcript in mutants. (J:114971)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpbar1 Mutation: 30 strains or lines available

References

• Original: J:114971 Maruyama T, et al., Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice. J Endocrinol. 2006 Oct;191(1):197-205
• All: 1 reference(s)