Nit1^tm1.1Hbn
Targeted Allele Detail

Summary

• Symbol: Nit1^tm1.1Hbn
• Name: nitrilase 1; targeted mutation 1, Kay Huebner
• MGI ID: MGI:3691199
• Synonyms: Nit1^-
• Gene: Nit1 Location: Chr1:171168145-171173209 bp, - strand Genetic Position: Chr1, 79.35 cM
• Alliance: Nit1^tm1.1Hbn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115052
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Nit1^tm1Hbn mice were crossed with Tg(EIIa-cre)C5379Lmgd mice to remove exons 4-7. (J:115052)

Tumor Data

List all tumor models in MMHCdb carrying Nit1^tm1.1Hbn

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nit1 Mutation: 15 strains or lines available

References

• Original: J:115052 Semba S, et al., Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor. J Biol Chem. 2006 Sep 22;281(38):28244-53
• All: 4 reference(s)