Bmper^tm2Ysas
Targeted Allele Detail

Summary

• Symbol: Bmper^tm2Ysas
• Name: BMP-binding endothelial regulator; targeted mutation 2, Yoshiki Sasai
• MGI ID: MGI:3691855
• Gene: Bmper Location: Chr9:23134372-23396496 bp, + strand Genetic Position: Chr9, 9.55 cM, cytoband A4
• Alliance: Bmper^tm2Ysas page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115338
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first metionine was replaced in-frame with that of beta-galactosidase with a nuclear localizing signal. (J:115338)

Expression

In Structures Affected by this Mutation:

21 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bmper Mutation: 47 strains or lines available

References

• Original: J:115338 Ikeya M, et al., Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis. Development. 2006 Nov;133(22):4463-73
• All: 1 reference(s)