Grin1^tm1Yql
Targeted Allele Detail

Summary

• Symbol: Grin1^tm1Yql
• Name: glutamate receptor, ionotropic, NMDA1 (zeta 1); targeted mutation 1, Yuqing Li
• MGI ID: MGI:3692441
• Synonyms: Flox-A, NMDAR1-loxP
• Gene: Grin1 Location: Chr2:25181193-25209199 bp, - strand Genetic Position: Chr2, 17.14 cM
• Alliance: Grin1^tm1Yql page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115299
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A targeting construct was designed to flank exons 9 and 10 with loxP sites. (J:115299)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grin1 Mutation: 66 strains or lines available

References

• Original: J:115299 Dang MT, et al., Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15254-9
• All: 12 reference(s)