Pawr^tm1Lht
Targeted Allele Detail

Summary

• Symbol: Pawr^tm1Lht
• Name: PRKC, apoptosis, WT1, regulator; targeted mutation 1, Li-Huei Tsai
• MGI ID: MGI:3692443
• Synonyms: Par-4deltaLZ
• Gene: Pawr Location: Chr10:108167982-108250101 bp, + strand Genetic Position: Chr10, 56.43 cM, cytoband D1
• Alliance: Pawr^tm1Lht page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115199
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Disruption caused by insertion of vector
• Mutation details: Exons 4 and 5 were removed by homologous recombination and resulted in a truncated protein lacking expression of the C-terminal leucine zipper region. (J:115199)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pawr Mutation: 20 strains or lines available

References

• Original: J:115199 Park SK, et al., Par-4 links dopamine signaling and depression. Cell. 2005 Jul 29;122(2):275-87
• All: 1 reference(s)