Camta2^tm1Eno
Targeted Allele Detail

Summary

• Symbol: Camta2^tm1Eno
• Name: calmodulin binding transcription activator 2; targeted mutation 1, Eric N Olson
• MGI ID: MGI:3692751
• Synonyms: Camta2^-
• Gene: Camta2 Location: Chr11:70560289-70578931 bp, - strand Genetic Position: Chr11, 43.21 cM
• Alliance: Camta2^tm1Eno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115868
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to remove amino acids 5-554, encoded by exons 3-10, and insertion of a lacZ reporter in-frame with amino acid 4. Absence of transcript was confirmed by RT-PCR. Immunostaining detected expression of the lacZ gene. (J:115868)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Camta2 Mutation: 43 strains or lines available

References

• Original: J:115868 Song K, et al., The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases. Cell. 2006 May 5;125(3):453-66
• All: 1 reference(s)