Tbx5^tm1.2Jse
Targeted Allele Detail

Summary

• Symbol: Tbx5^tm1.2Jse
• Name: T-box 5; targeted mutation 1.2, Jonathan G Seidman
• MGI ID: MGI:3692758
• Synonyms: Tbx5^LDN
• Gene: Tbx5 Location: Chr5:119970733-120023284 bp, + strand Genetic Position: Chr5, 60.42 cM
• Alliance: Tbx5^tm1.2Jse page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112887
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: This allele resulted from the cre-mediated removal of the floxed neo in Tbx5^tm1Jse, leaving exon 3 flanked with loxP sites. (J:112887)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx5 Mutation: 29 strains or lines available

References

• Original: J:112887 Mori AD, et al., Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis. Dev Biol. 2006 Sep 15;297(2):566-86
• All: 10 reference(s)