Satb2^tm1Rug
Targeted Allele Detail

Summary

• Symbol: Satb2^tm1Rug
• Name: special AT-rich sequence binding protein 2; targeted mutation 1, Rudolf Grosschedl
• MGI ID: MGI:3692768
• Synonyms: Satb2^-, Satb2^LacZ
• Gene: Satb2 Location: Chr1:56833140-57017809 bp, - strand Genetic Position: Chr1, 28.72 cM
• Alliance: Satb2^tm1Rug page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115876
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A betagalactosidase/pgk-neo cassette was inserted in frame with the ATG codon in exon 2. Immunoblot confirmed absence of protein in mutant mice. (J:115876)

Expression

In Mice Carrying this Mutation:	127 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	20 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Satb2 Mutation: 43 strains or lines available

References

• Original: J:115876 Dobreva G, et al., SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell. 2006 Jun 2;125(5):971-86
• All: 12 reference(s)