Or8a1^tm28(cre)Mom
Targeted Allele Detail

Summary

• Symbol: Or8a1^tm28(cre)Mom
• Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 28, Peter Mombaerts
• MGI ID: MGI:3692997
• Synonyms: M71-IRES-Cre, M71(Olfr151)^cre
• Gene: Or8a1 Location: Chr9:37641273-37642357 bp, - strand Genetic Position: Chr9, 20.8 cM
• Alliance: Or8a1^tm28(cre)Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115857
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Or8a1^tm28(cre)Mom expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Or8a1 (MGI:2661338)

• Mutation details: An IRES-cre-FNF cassette was inserted downstream of the coding sequence of Olfr151 to permit bicistronic expression of Olfr151 and cre recombinase. The neo cassette was excised by crossing to mice bearing Tg(ACTB-FLP). (J:115857)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Or8a1 (mouse) Summary of all recombinase alleles driven by Or8a1. Comparative matrix view of recombinase activities Alliance mouse Or8a1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Or8a1 Mutation: 69 strains or lines available

References

• Original: J:115857 Li J, et al., Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons. Nature. 2004 Mar 25;428(6981):393-9
• All: 6 reference(s)