Tg(Tal1-tTA)19Dgt
Transgene Detail

Summary

• Symbol: Tg(Tal1-tTA)19Dgt
• Name: transgene insertion 19, Daniel G Tenen
• MGI ID: MGI:3693328
• Synonyms: Scl-tTA, SCLtTA, SCLtTA stg
• Transgene: Tg(Tal1-tTA)19Dgt Location: unknown
• Alliance: Tg(Tal1-tTA)19Dgt page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The transgene consists of the SV40 minimal promoter, rabbit beta-globin intron 2, and the 3' enhancer sequence from the mouse T-cell acute lymphocytic leukemia gene driving expression of the tetracycline-regulated transactivator. (J:96511)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:96511 Koschmieder S, et al., Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis. Blood. 2005 Jan 1;105(1):324-34
• All: 45 reference(s)