Chaf1a^tm1Ger
Targeted Allele Detail

Summary

• Symbol: Chaf1a^tm1Ger
• Name: chromatin assembly factor 1, subunit A; targeted mutation 1, Matthieu Gerard
• MGI ID: MGI:3693625
• Synonyms: Chaf1a^-
• Gene: Chaf1a Location: Chr17:56347404-56375027 bp, + strand Genetic Position: Chr17, 29.13 cM, cytoband D
• Alliance: Chaf1a^tm1Ger page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116133
• Parent Cell Line: AT1 (ES Cell)
• Strain of Origin: 129S2/SvPasCrl

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 3 was replaced by a neomycin resistance cassette. (J:116133)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chaf1a Mutation: 46 strains or lines available

References

• Original: J:116133 Houlard M, et al., CAF-1 is essential for heterochromatin organization in pluripotent embryonic cells. PLoS Genet. 2006 Nov 3;2(11):e181
• All: 1 reference(s)