Ednrb^tm1Yko
Targeted Allele Detail

Summary

• Symbol: Ednrb^tm1Yko
• Name: endothelin receptor type B; targeted mutation 1, Yuri Kotelevtsev
• MGI ID: MGI:3693642
• Gene: Ednrb Location: Chr14:104052055-104081764 bp, - strand Genetic Position: Chr14, 53.05 cM
• Alliance: Ednrb^tm1Yko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116002
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank exons 3 and 4. (J:116002)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ednrb Mutation: 104 strains or lines available

References

• Original: J:116002 Ge Y, et al., Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention. Am J Physiol Renal Physiol. 2006 Dec;291(6):F1274-80
• All: 9 reference(s)