Slc17a6^tm1Kldr
Targeted Allele Detail

Summary

• Symbol: Slc17a6^tm1Kldr
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1, Klas Kullander
• MGI ID: MGI:3693864
• Synonyms: Vglut2^f
• Gene: Slc17a6 Location: Chr7:51271754-51320867 bp, + strand Genetic Position: Chr7, 32.78 cM, cytoband B4
• Alliance: Slc17a6^tm1Kldr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116180
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 4-6 were flanked by an upstream loxP site and a downstream FRT-flanked neo followed by a loxP site. The neo was removed by crossing with mice expressing FLP recombinase. (J:116180)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc17a6 Mutation: 60 strains or lines available

References

• Original: J:116180 Wallen-Mackenzie A, et al., Vesicular glutamate transporter 2 is required for central respiratory rhythm generation but not for locomotor central pattern generation. J Neurosci. 2006 Nov 22;26(47):12294-307
• All: 18 reference(s)