Adcy7^tm1Btab
Targeted Allele Detail

Summary

• Symbol: Adcy7^tm1Btab
• Name: adenylate cyclase 7; targeted mutation 1, Boris Tabakoff
• MGI ID: MGI:3693867
• Synonyms: Adcy7^-
• Gene: Adcy7 Location: Chr8:88999031-89056590 bp, + strand Genetic Position: Chr8, 43.06 cM
• Alliance: Adcy7^tm1Btab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116184
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Exon 3, which encodes part of the highly conserved C1a domain of the protein, was disrupted. (J:116184)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adcy7 Mutation: 60 strains or lines available

References

• Original: J:116184 Hines LM, et al., A sex-specific role of type VII adenylyl cyclase in depression. J Neurosci. 2006 Nov 29;26(48):12609-19
• All: 3 reference(s)