Slc17a6^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Slc17a6^tm1Lex
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3693887
• Synonyms: Vglut2^-
• Gene: Slc17a6 Location: Chr7:51271754-51320867 bp, + strand Genetic Position: Chr7, 32.78 cM, cytoband B4
• Alliance: Slc17a6^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116159
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• An IRES-betageo-PGKpuro replaced exon 2, resulting in the disruption of the reading frame. (J:116159)

Expression

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc17a6 Mutation: 60 strains or lines available

References

• Original: J:116159 Moechars D, et al., Vesicular glutamate transporter VGLUT2 expression levels control quantal size and neuropathic pain. J Neurosci. 2006 Nov 15;26(46):12055-66
• All: 9 reference(s)