Epha4^tm1Pvan
Targeted Allele Detail

Summary

• Symbol: Epha4^tm1Pvan
• Name: Eph receptor A4; targeted mutation 1, Pierre Vanderhaeghen
• MGI ID: MGI:3693889
• Synonyms: EphA4^deltaPBM
• Gene: Epha4 Location: Chr1:77343822-77491725 bp, - strand Genetic Position: Chr1, 39.55 cM, cytoband C1-C5
• Alliance: Epha4^tm1Pvan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115279
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Disruption caused by insertion of vector
• The last 12 amino acids, including the PDZ domain, were removed from the locus. (J:115279)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epha4 Mutation: 67 strains or lines available

References

• Original: J:115279 Dufour A, et al., Genetic analysis of EphA-dependent signaling mechanisms controlling topographic mapping in vivo. Development. 2006 Nov;133(22):4415-20
• All: 4 reference(s)