Catsper3^tm1Clph
Targeted Allele Detail

Summary

• Symbol: Catsper3^tm1Clph
• Name: cation channel, sperm associated 3; targeted mutation 1, David E Clapham
• MGI ID: MGI:3694352
• Gene: Catsper3 Location: Chr13:55932381-55956811 bp, + strand Genetic Position: Chr13, 30.06 cM, cytoband B2
• Alliance: Catsper3^tm1Clph page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116406
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4-7, including sequences encoding the putative pore region and part of the C-terminus of the protein, have been replaced by a neomycin resistance cassette. (J:116406)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Catsper3 Mutation: 28 strains or lines available

References

• Original: J:116406 Qi H, et al., All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1219-23
• All: 1 reference(s)