Apba2^tm1.1Sud
Targeted Allele Detail

Summary

• Symbol: Apba2^tm1.1Sud
• Name: amyloid beta precursor protein binding family A member 2; targeted mutation 1.1, Thomas C Sudhof
• MGI ID: MGI:3694702
• Synonyms: conditional KO, Flp-Recombined, M2F
• Gene: Apba2 Location: Chr7:64151454-64403626 bp, + strand Genetic Position: Chr7, 34.65 cM
• Alliance: Apba2^tm1.1Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115573
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: In offspring of these mice generated by crossing to germline Cre recombinase-expressing mice, expression is completely ablated. (J:115573)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apba2 Mutation: 45 strains or lines available

References

• Original: J:115573 Ho A, et al., Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family. J Neurosci. 2006 Dec 13;26(50):13089-101
• All: 2 reference(s)