Kcna5^tm1Hket
Targeted Allele Detail

Summary

• Symbol: Kcna5^tm1Hket
• Name: potassium voltage-gated channel, shaker-related subfamily, member 5; targeted mutation 1, Helmut Kettenmann
• MGI ID: MGI:3694764
• Synonyms: Kv1.5^-
• Gene: Kcna5 Location: Chr6:126509514-126512375 bp, - strand Genetic Position: Chr6, 61.35 cM
• Alliance: Kcna5^tm1Hket page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116545
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The translational start site and most of the open reading frame was replaced with a neomycin resistance cassette. (J:116545)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcna5 Mutation: 34 strains or lines available

References

• Original: J:116545 Pannasch U, et al., The potassium channels Kv1.5 and Kv1.3 modulate distinct functions of microglia. Mol Cell Neurosci. 2006 Dec 15;33(4):401-411
• All: 2 reference(s)