Amelx^tm2Msnd
Targeted Allele Detail

Summary

• Symbol: Amelx^tm2Msnd
• Name: amelogenin, X-linked; targeted mutation 2, Malcolm L Snead
• MGI ID: MGI:3694787
• Synonyms: deltaB
• Gene: Amelx Location: ChrX:167959110-167970196 bp, - strand Genetic Position: ChrX, 78.95 cM
• Alliance: Amelx^tm2Msnd page

Enamel architecture changes in Amelx^tm1Msnd/Amelx^tm1Msnd and Amelx^tm2Msnd/Amelx^tm2Msnd mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116448
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a minigene lacking a carboxyl-terminal conserved domain defined by residues 157-173. (J:116448)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Amelx Mutation: 26 strains or lines available

References

• Original: J:116448 Zhu D, et al., Altering biomineralization by protein design. J Biol Chem. 2006 Jul 28;281(30):21173-82
• All: 1 reference(s)