Arhgap32^tm1Taki
Targeted Allele Detail

Summary

• Symbol: Arhgap32^tm1Taki
• Name: Rho GTPase activating protein 32; targeted mutation 1, Tetsu Akiyama
• MGI ID: MGI:3694810
• Synonyms: PX-RICS^-, RICS^-
• Gene: Arhgap32 Location: Chr9:32027432-32179742 bp, + strand Genetic Position: Chr9, 17.48 cM
• Alliance: Arhgap32^tm1Taki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116446
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A lacZ-neo cassette was inserted at the ATG. Western blot failed to detect protein in mutant mice. (J:116446)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgap32 Mutation: 87 strains or lines available

Notes

Phenotypic Similarity to Human Syndrome: Autism Spectrum Disorder in Jacobsen Syndrome J: 236753.

References

• Original: J:116446 Nasu-Nishimura Y, et al., Role of the Rho GTPase-activating protein RICS in neurite outgrowth. Genes Cells. 2006 Jun;11(6):607-14
• All: 2 reference(s)