Gfi1^{tm3(Gfib1)Tmo}
Targeted Allele Detail

Summary

• Symbol: Gfi1^{tm3(Gfib1)Tmo}
• Name: growth factor independent 1 transcription repressor; targeted mutation 3, Tarik Moroy
• MGI ID: MGI:3695403
• Synonyms: Gfi1:Gfi1b
• Gene: Gfi1 Location: Chr5:107864521-107873671 bp, - strand Genetic Position: Chr5, 52.23 cM
• Alliance: Gfi1^{tm3(Gfib1)Tmo} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116870
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• The coding region was replaced with growth factor independent 1B cDNA. (J:116870)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gfi1 Mutation: 31 strains or lines available

References

• Original: J:116870 Fiolka K, et al., Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development. EMBO Rep. 2006 Mar;7(3):326-33
• All: 1 reference(s)