Krt4^Bcc1
Chemically induced Allele Detail

Summary

• Symbol: Krt4^Bcc1
• Name: keratin 4; bright coat color 1
• MGI ID: MGI:3695408
• Synonyms: Bcc1
• Gene: Krt4 Location: Chr15:101826970-101833170 bp, - strand Genetic Position: Chr15, 57.13 cM
• Alliance: Krt4^Bcc1 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• An A to G transition in exon 1 resulted in an N154S missense alteration in the 1A domain. (J:116740)
• Inheritance: Dominant

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Krt4 Mutation: 19 strains or lines available

References

• Original: J:116740 McGowan KA, et al., Identification of a Keratin 4 mutation in a chemically induced mouse mutant that models white sponge nevus. J Invest Dermatol. 2007 Jan;127(1):60-4
• All: 1 reference(s)