Satb2^tm1(cre)Vit
Targeted Allele Detail

Summary

• Symbol: Satb2^tm1(cre)Vit
• Name: special AT-rich sequence binding protein 2; targeted mutation 1, Victor Tarabykin
• MGI ID: MGI:3695425
• Synonyms: Satb2^-
• Gene: Satb2 Location: Chr1:56833140-57017809 bp, - strand Genetic Position: Chr1, 28.72 cM
• Alliance: Satb2^tm1(cre)Vit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116770
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Satb2^tm1(cre)Vit expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Satb2 (MGI:2679336)

• Exon 2 was replaced with cre recombinase cDNA and a neomycin resistance cassette. (J:116770)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Satb2 (mouse) Summary of all recombinase alleles driven by Satb2. Alliance mouse Satb2 gene page

Disease models

Expression

In Mice Carrying this Mutation:	21 assay results
In Structures Affected by this Mutation:	12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Satb2 Mutation: 43 strains or lines available

References

• Original: J:116770 Britanova O, et al., Satb2 haploinsufficiency phenocopies 2q32-q33 deletions, whereas loss suggests a fundamental role in the coordination of jaw development. Am J Hum Genet. 2006 Oct;79(4):668-78
• All: 8 reference(s)