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Tg(Amelx-Dspp)13Mlp
Transgene Detail
Summary
Symbol: Tg(Amelx-Dspp)13Mlp
Name: transgene insertion 13, Michael L Paine
MGI ID: MGI:3695684
Synonyms: MYC-DPP, Tg(Amelx-Dspp/Dpp)13Mlp
Transgene: Tg(Amelx-Dspp)13Mlp  Location: unknown  
Alliance: Tg(Amelx-Dspp)13Mlp page
Transgene
origin
Strain of Origin:  (C57BL/6J x DBA/2J)F1 x CBA/J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Amelx-Dspp)13Mlp expresses 1 gene
 
Mutation detailsThe mouse amelogenin promoter was used to drive expression of dentin phosphoprotein ectopically in the enamel organ. Mice derived from line 13 are representative of lines 10, 46, and 53. all of which carry a single copy of the inserted transgene construct. Line 47 carries more than 10 and probably around 23 copies of the insert and displays a diverging phenotype. (J:101218)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:101218 Paine ML, et al., Dentin sialoprotein and dentin phosphoprotein overexpression during amelogenesis. J Biol Chem. 2005 Sep 9;280(36):31991-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory