Otx2^tm1.1Tlam
Targeted Allele Detail

Summary

• Symbol: Otx2^tm1.1Tlam
• Name: orthodenticle homeobox 2; targeted mutation 1.1, Thomas Lamonerie
• MGI ID: MGI:3695699
• Synonyms: Otx2^flox
• Gene: Otx2 Location: Chr14:48894238-48905101 bp, - strand Genetic Position: Chr14, 25.36 cM
• Alliance: Otx2^tm1.1Tlam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116888
• Parent Cell Line: ENS (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank exon 2. (J:116888)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Otx2 Mutation: 50 strains or lines available

References

• Original: J:116888 Fossat N, et al., Temporal and spatial delineation of mouse Otx2 functions by conditional self-knockout. EMBO Rep. 2006 Aug;7(8):824-30
• All: 12 reference(s)