Map3k7^tm1.1Mds
Targeted Allele Detail

Summary

• Symbol: Map3k7^tm1.1Mds
• Name: mitogen-activated protein kinase kinase kinase 7; targeted mutation 1.1, Michael D Schneider
• MGI ID: MGI:3696053
• Gene: Map3k7 Location: Chr4:31964097-32023467 bp, + strand Genetic Position: Chr4, 13.91 cM
• Alliance: Map3k7^tm1.1Mds page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117108
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 1 was removed via cre-mediated recombination. (J:117108)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Map3k7 Mutation: 54 strains or lines available

References

• Original: J:117108 Xie M, et al., A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17378-83
• All: 2 reference(s)