Or8a1tm32Mom
Targeted Allele Detail
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Symbol: |
Or8a1tm32Mom |
Name: |
olfactory receptor family 8 subfamily A member 1; targeted mutation 32, Peter Mombaerts |
MGI ID: |
MGI:3696077 |
Synonyms: |
M71(Horp)-lacZ |
Gene: |
Or8a1 Location: Chr9:37641273-37642357 bp, - strand Genetic Position: Chr9, 20.8 cM
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Alliance: |
Or8a1tm32Mom page
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Germline Transmission: |
Earliest citation of germline transmission:
J:115911
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Reporter) |
Mutation: |
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Insertion
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Mutation details: A 39 bp segment of the promotor, containing the homeodomain and the O/E-like binding sites, was replaced with a 17 bp segment from the Olfr155 promotor region and an IRES-taulacZ-ACNf cassette was inserted immediately following the endogenous stop codon. The ACNf cassette self-excised in the male germline leaving no neo sequence.
(J:115911)
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Key: |
hm |
homozygous |
ht |
heterozygous |
tg |
involves transgenes |
√ |
phenotype observed |
cn |
conditional genotype |
cx |
complex: > 1 genome feature |
ot |
other: hemizygous, indeterminate,... |
N |
normal phenotype |
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Genotype/ Background: |
| Allelic Composition | Genetic Background | Cell Line(s) |
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Loading... | | | involves: 129P2/OlaHsd * C57BL/6J | |
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Phenotypes: |
Affected Systems |
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nervous system
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√
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abnormal olfactory bulb morphology
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√
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Or8a1 Mutation: |
69 strains or lines available
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Original: |
J:115911 Rothman A, et al., The promoter of the mouse odorant receptor gene M71. Mol Cell Neurosci. 2005 Mar;28(3):535-46 |
All: |
1 reference(s) |
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