Tg(ACTB-DDAH1)1Jpck
Transgene Detail

Summary

• Symbol: Tg(ACTB-DDAH1)1Jpck
• Name: transgene insertion 1, John P Cooke
• MGI ID: MGI:3696379
• Synonyms: DDAH, DDAH1 TG
• Transgene: Tg(ACTB-DDAH1)1Jpck Location: unknown
• Alliance: Tg(ACTB-DDAH1)1Jpck page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTB-DDAH1)1Jpck expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  DDAH1 (23576)

  Ddah1

  (MGI:1916469)

• Mutation details: A human DDAH-I cDNA and SV40 derived from a modified human agouti expression vector were placed under control of the human B-actin promoter. (J:104238)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:104238 Dayoub H, et al., Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. Circulation. 2003 Dec 16;108(24):3042-7
• All: 17 reference(s)