Acvr1^tm1.1Vk
Targeted Allele Detail

Summary

• Symbol: Acvr1^tm1.1Vk
• Name: activin A receptor, type 1; targeted mutation 1.1, Vesa Kaartinen
• MGI ID: MGI:3696672
• Synonyms: Acvr1^fx(exon7), Alk2^delta7
• Gene: Acvr1 Location: Chr2:58336450-58456840 bp, - strand Genetic Position: Chr2, 33.05 cM
• Alliance: Acvr1^tm1.1Vk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:73148
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 7 was removed via cre mediated recombination in Acvr1^tm1Vk mutants. (J:73148)

Expression

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	31 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Acvr1 Mutation: 44 strains or lines available

References

• Original: J:73148 Kaartinen V, et al., Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo. Genesis. 2001 Nov;31(3):126-9
• All: 7 reference(s)