Zglp1^tm1Eem
Targeted Allele Detail

Summary

• Symbol: Zglp1^tm1Eem
• Name: zinc finger, GATA-like protein 1; targeted mutation 1, Edward E Morrisey
• MGI ID: MGI:3696745
• Synonyms: Glp-1^lacZ
• Gene: Zglp1 Location: Chr9:20973689-20978389 bp, - strand Genetic Position: Chr9, 7.7 cM
• Alliance: Zglp1^tm1Eem page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116977
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace all five exons with the beta-galactosidase cDNA and the neomycin resistance cassette. The neo was subsequently removed via cre mediated recombination. (J:116977)

Expression

In Mice Carrying this Mutation:	24 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zglp1 Mutation: 13 strains or lines available

References

• Original: J:116977 Li S, et al., GLP-1: a novel zinc finger protein required in somatic cells of the gonad for germ cell development. Dev Biol. 2007 Jan 1;301(1):106-16
• All: 4 reference(s)