Sfrp5^tm1Shwl
Targeted Allele Detail

Summary

• Symbol: Sfrp5^tm1Shwl
• Name: secreted frizzled-related sequence protein 5; targeted mutation 1, William Shawlot
• MGI ID: MGI:3696766
• Synonyms: Sfrp5^-
• Gene: Sfrp5 Location: Chr19:42186410-42190691 bp, - strand Genetic Position: Chr19, 35.93 cM, cytoband D1
• Alliance: Sfrp5^tm1Shwl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117057
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced most of the coding sequence. (J:117057)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sfrp5 Mutation: 27 strains or lines available

References

• Original: J:117057 Leaf I, et al., Sfrp5 is not essential for axis formation in the mouse. Genesis. 2006 Dec;44(12):573-8
• All: 1 reference(s)