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Atp1a3tm1Ling
Targeted Allele Detail
Summary
Symbol: Atp1a3tm1Ling
Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide; targeted mutation 1, Jerry B Lingrel
MGI ID: MGI:3696954
Synonyms: Alpha3-
Gene: Atp1a3  Location: Chr7:24677592-24705338 bp, - strand  Genetic Position: Chr7, 13.73 cM
Alliance: Atp1a3tm1Ling page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117414
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Nucleotide substitutions
 
Mutation detailsA single base pair mutation in intron 4 adjacent to the exon-intron splice site resulted in aberrant splicing of the gene, adding 126 base pairs to the transcript. (J:117414)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atp1a3 Mutation:  70 strains or lines available
References
Original:  J:117414 Moseley AE, et al., Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice. J Neurosci. 2007 Jan 17;27(3):616-26
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory