Cacna1a^tm2.2Maag
Targeted Allele Detail

Summary

• Symbol: Cacna1a^tm2.2Maag
• Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; targeted mutation 2.2, Arn van den Maagdenberg
• MGI ID: MGI:3696967
• Synonyms: Cacna1a^deltaE4
• Gene: Cacna1a Location: Chr8:85065268-85366875 bp, + strand Genetic Position: Chr8, 40.95 cM
• Alliance: Cacna1a^tm2.2Maag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117062
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 4 was removed via cre mediated recombination in the germline. (J:117062)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cacna1a Mutation: 118 strains or lines available

References

• Original: J:117062 Todorov B, et al., Conditional inactivation of the Cacna1a gene in transgenic mice. Genesis. 2006 Dec;44(12):589-94
• All: 1 reference(s)