Sox13tm1Jskg
Targeted Allele Detail
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Symbol: |
Sox13tm1Jskg |
Name: |
SRY (sex determining region Y)-box 13; targeted mutation 1, Joonsoo Kang |
MGI ID: |
MGI:3697320 |
Synonyms: |
Sox13- |
Gene: |
Sox13 Location: Chr1:133310041-133352115 bp, - strand Genetic Position: Chr1, 57.91 cM
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Alliance: |
Sox13tm1Jskg page
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Germline Transmission: |
Earliest citation of germline transmission:
J:117301
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: A floxed neo was inserted into intron 3 and an additional loxP site was inserted into intron 11. A ~500 bp deletion was created in intron 5 for ES cell screening purposes. Transient cre expression resulted in the deletion of exons 4-11. Semi-quantitative RT-PCR confirmed lack of expression in mutant thymus.
(J:117301)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Sox13 Mutation: |
58 strains or lines available
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Original: |
J:117301 Melichar HJ, et al., Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13. Science. 2007 Jan 12;315(5809):230-3 |
All: |
4 reference(s) |
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