Mad1l1^tm1.1Ktj
Targeted Allele Detail

Summary

• Symbol: Mad1l1^tm1.1Ktj
• Name: MAD1 mitotic arrest deficient 1-like 1; targeted mutation 1.1, Kuan-Teh Jeang
• MGI ID: MGI:3697324
• Synonyms: Mad1^-
• Gene: Mad1l1 Location: Chr5:139994444-140307307 bp, - strand Genetic Position: Chr5, 78.82 cM
• Alliance: Mad1l1^tm1.1Ktj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117337
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 10 was removed via cre-mediated recombination in the germline. (J:117337)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Mad1l1^tm1.1Ktj

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mad1l1 Mutation: 65 strains or lines available

References

• Original: J:117337 Iwanaga Y, et al., Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice. Cancer Res. 2007 Jan 1;67(1):160-6
• All: 2 reference(s)