Tg(CAG-Tle1,-ALPP)1Lbe
Transgene Detail

Summary

• Symbol: Tg(CAG-Tle1,-ALPP)1Lbe
• Name: transgene insertion 1, Corrinne Lobe
• MGI ID: MGI:3697397
• Synonyms: Grg1^hPLAP, Tg(ACTB-Tle1,-ALPP)1Lbe, Tg(CAG-Tle1,-ALPP)1Lbe
• Transgene: Tg(CAG-Tle1,-ALPP)1Lbe Location: unknown
• Alliance: Tg(CAG-Tle1,-ALPP)1Lbe page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:106684
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Tle1,-ALPP)1Lbe expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tle1 (MGI:104636)

• Mutation details: When the conditional transgene Tg(CAG-Bgeo,-Tle1,-ALPP)1Lbe is modified by in vivo excision of Bgeo by cre recombinase, Tle1 and ALPP expression results, and this modified transgene is transmitted to offspring in absence of cre. (J:106684)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:106684 Allen T, et al., Grg1 acts as a lung-specific oncogene in a transgenic mouse model. Cancer Res. 2006 Feb 1;66(3):1294-301
• All: 1 reference(s)