Myot^tm1.1Moza
Targeted Allele Detail

Summary

• Symbol: Myot^tm1.1Moza
• Name: myotilin; targeted mutation 1.1, Monica Moza
• MGI ID: MGI:3697714
• Synonyms: Myo^-
• Gene: Myot Location: Chr18:44467141-44488791 bp, + strand Genetic Position: Chr18, 23.74 cM, cytoband B3
• Alliance: Myot^tm1.1Moza page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117709
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 3 was removed via cre-mediated recombination. Neither full length nor truncated protein was detected in mutants. (J:117709)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myot Mutation: 28 strains or lines available

References

• Original: J:117709 Moza M, et al., Targeted deletion of the muscular dystrophy gene myotilin does not perturb muscle structure or function in mice. Mol Cell Biol. 2007 Jan;27(1):244-52
• All: 2 reference(s)