Drd3^tm1Rmw
Targeted Allele Detail

Summary

• Symbol: Drd3^tm1Rmw
• Name: dopamine receptor D3; targeted mutation 1, R M Wightman
• MGI ID: MGI:3698033
• Synonyms: D3-KO
• Gene: Drd3 Location: Chr16:43574389-43643295 bp, + strand Genetic Position: Chr16, 28.44 cM
• Alliance: Drd3^tm1Rmw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117918
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was replaced by a PGK-neo cassette. (J:117918)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Drd3 Mutation: 59 strains or lines available

References

• Original: J:117918 Joseph JD, et al., Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors. Neuroscience. 2002;112(1):39-49
• All: 8 reference(s)