Hadhb^m1Ytc
Chemically induced Allele Detail

Summary

• Symbol: Hadhb^m1Ytc
• Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; mutation 1, Yuan-Tsong Chen
• MGI ID: MGI:3698125
• Synonyms: Hadhb^m1Yuan
• Gene: Hadhb Location: Chr5:30360251-30389591 bp, + strand Genetic Position: Chr5, 16.04 cM
• Alliance: Hadhb^m1Ytc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This allele contains a missense mutation of methionine to lysine at amino acid 404, resulting from a T-to-A transversion in exon 14. (J:117738)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hadhb Mutation: 31 strains or lines available

References

• Original: J:117738 Kao HJ, et al., ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit. Hum Mol Genet. 2006 Dec 15;15(24):3569-77
• All: 1 reference(s)